How Stress can lead to Depression

A new study, conducted by the Icahn School of Medicine at Mount Sinai, revealed data suggesting that pre-existing individual differences in the peripheral immune system predicted and promoted stress susceptibility. These findings, published in the Proceedings of the National Academy of Sciences (PNAS) also suggested that inflammation caused by stress may increase the risk of depression. The research results offer the potential for new treatment for stress disorders, and new therapeutic strategies to reengineer a patient’s immune system to reduce stress vulnerability. Lifestyle changes, such as eating a balanced diet and regular exercise, are recommended to reduce stress in a positive, heart-healthy way.

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