How are Depression and Memory Loss Connected?

A new study, published in the latest edition of Psychoneuroendocrinology, delves more deeply into the relationship between depression and memory loss, and how this connection may depend on levels of insulin-like growth factor, or IGF-1. Prior research has shown that IGF-1, a hormone that helps bolster growth, is important for preserving memory, especially among older adults. The collaborative study, conducted by the University of Rochester School of Medicine and Dentistry and the School of Nursing, found that people with lower cognitive ability were more likely to have higher depressive symptoms if they also had low levels of IGF-1. Reversely, participants with high levels of IGF-1 had no link between depressive symptoms and memory.

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