Genes in the Brain Keep Bad Time when We are Depressed

It is known that genes in cells throughout the body switch on and off throughout the day, in a coordinated way, when working properly. In people with clinical depression, genes in their brain tissues appear to be significantly out of sync, according to a study conducted at the University of Michigan in Ann Arbor. By examining the genetic state of the brain in someone who had recently died, the research team could correctly determine the time of death – unless that person had depression. The brains of people who had been diagnosed with major depressive disorder before they died had far fewer genes following a regular cycle.

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