Bipolar Disorder Treatment Nonadherence Needs Attention

More than half of patients with bipolar disorder fail to take their medication as prescribed, according to a Finish study conducted with both inpatients and outpatients. The most common reasons for nonadherence given by patients were side effects, lack of motivation, and a negative attitude toward the particular treatment. A low educational attainment was also a significant predictor of nonadherence. Given the profound clinical implications of nonadherence, the authors call for patients’ attitudes toward their medication to be closely monitored. Writing in the Journal of Affective Disorders, they note that “pharmacological treatments were autonomously discontinued by one-quarter of patients, and of the medication continued, one third were not used regularly enough to provide a benefit.”

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